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具有 Nanopartz™ 共價鍵合聚合物的功能化金納米顆粒
下表顯示了使用 PEG 作為共價聚合物橋的金納米顆粒上 IgG 的典型負載量。我們的體外聚合物是原來的 2 倍。我們的體內(nèi)聚合物含量高出約 50%。
球體吸收
部分 ＃ | 直徑（納米） | 峰值SPR（納米） | NPS/毫升 | 摩爾濃度 (pM) | 痣 | IgG抗體/np | 總（和）IgG |
CA11-1.8 | 1.8 | 不適用 | 4.25E+16 | 7.10E+07 | 7.09E-08 | 0.1 | 1,379 |
CA11-2.2 | 2.2 | 不適用 | 2.33E+16 | 3.90E+07 | 3.88E-08 | 0.2 | 1,128 |
CA11-3 | 3 | 不適用 | 9.19E+15 | 1.50E+07 | 1.53E-08 | 0.4 | 827 |
CA11-4 | 4 | 不適用 | 3.88E+15 | 6.50E+06 | 6.46E-09 | 0.6 | 620 |
CA11-5 | 5 | 512 | 1.99E+15 | 3.30E+06 | 3.31E-09 | 1 | 496 |
CA11-10 | 10 | 516 | 2.48E+14 | 4.10E+05 | 4.14E-10 | 4 | 248 |
CA11-15 | 15 | 518 | 7.35E+13 | 1.20E+05 | 1.23E-10 | 9 | 165 |
CA11-20 | 20 | 520 | 3.10E+13 | 5.20E+04 | 5.17E-11 | 16 | 124 |
CA11-25 | 25 | 521 | 1.59E+13 | 2.60E+04 | 2.65E-11 | 25 | 99 |
CA11-30 | 30 | 523 | 9.19E+12 | 1.50E+04 | 1.53E-11 | 36 | 83 |
CA11-35 | 35 | 526 | 5.79E+12 | 9.60E+03 | 9.65E-12 | 49 | 71 |
CA11-40 | 40 | 527 | 3.88E+12 | 6.50E+03 | 6.46E-12 | 64 | 62 |
CA11-45 | 45 | 529 | 2.72E+12 | 4.50E+03 | 4.54E-12 | 81 | 55 |
CA11-50 | 50 | 531 | 1.99E+12 | 3.30E+03 | 3.31E-12 | 100 | 50 |
CA11-55 | 55 | 533 | 1.49E+12 | 2.50E+03 | 2.49E-12 | 121 | 45 |
CA11-60 | 60 | 536 | 1.15E+12 | 1.90E+03 | 1.91E-12 | 144 | 41 |
CA11-65 | 65 | 539 | 9.04E+11 | 1.50E+03 | 1.51E-12 | 169 | 38 |
CA11-70 | 70 | 542 | 7.23E+11 | 1.20E+03 | 1.21E-12 | 196 | 35 |
CA11-75 | 75 | 545 | 5.88E+11 | 9.80E+02 | 9.80E-13 | 225 | 33 |
CA11-80 | 80 | 549 | 4.85E+11 | 8.10E+02 | 8.08E-13 | 256 | 31 |
CA11-85 | 85 | 553 | 4.04E+11 | 6.70E+02 | 6.73E-13 | 289 | 29 |
CA11-90 | 90 | 558 | 3.40E+11 | 5.70E+02 | 5.67E-13 | 324 | 28 |
CA11-95 | 95 | 563 | 2.89E+11 | 4.80E+02 | 4.82E-13 | 361 | 26 |
CA11-100 | 100 | 569 | 2.48E+11 | 4.10E+02 | 4.14E-13 | 400 | 25 |
CA11-150 | 150 | 612 | 7.35E+10 | 1.20E+02 | 1.23E-13 | 900 | 17 號 |
CA11-200 | 200 | 不適用 | 3.10E+10 | 5.20E+01 | 5.17E-14 | 1600 | 12 |
CA11-500 | 500 | 不適用 | 1.99E+09 | 3.30E+00 | 3.31E-15 | 10000 | 5 |
CA11-1000 | 1000 | 不適用 | 2.48E+08 | 4.10E-01 | 4.14E-16 | 40000 | 2 |
CA11-1500 | 1500 | 不適用 | 7.35E+07 | 1.20E-01 | 1.23E-16 | 90000 | 2 |
納米棒抗體加載
部分 ＃ | 直徑（納米） | 長度（納米） | 峰值 SPR 波 (nm) | 縱橫比 | 從 SPR（澳大利亞）出發(fā) | IgG抗體/納米棒 | 總（和）IgG |
CA12-5-808 | 5 | 21 | 808 | 4.2 | 50 | 4 | 251 |
CA12-5-780 | 5 | 19 | 780 | 3.8 | 50 | 4 | 253 |
CA12-5-700 | 5 | 15 | 700 | 3 | 50 | 3 | 260 |
CA12-10-2100 | 10 | 175 | 2100 | 17.5 | 50 | 70 | 118 |
CA12-10-1400 | 10 | 102 | 1400 | 10.2 | 50 | 41 | 120 |
CA12-10-1200 | 10 | 81 | 1200 | 8.1 | 50 | 33 | 121 |
CA12-10-1064 | 10 | 67 | 1064 | 6.7 | 50 | 27 | 122 |
CA12-10-980 | 10 | 59 | 980 | 5.9 | 50 | 23 | 123 |
CA12-10-950 | 10 | 55 | 950 | 5.5 | 50 | 22 | 123 |
CA12-10-900 | 10 | 50 | 900 | 5 | 50 | 20 | 124 |
CA12-10-850 | 10 | 45 | 850 | 4.5 | 50 | 18 | 125 |
CA12-10-808 | 10 | 41 | 808 | 4.1 | 50 | 16 | 126 |
CA12-10-780 | 10 | 38 | 780 | 3.8 | 50 | 15 | 127 |
CA12-10-750 | 10 | 35 | 750 | 3.5 | 50 | 14 | 128 |
CA12-10-700 | 10 | 29 | 700 | 2.9 | 50 | 12 | 130 |
CA12-10-650 | 10 | 24 | 650 | 2.4 | 50 | 10 | 134 |
CA12-10-600 | 10 | 19 | 600 | 1.9 | 50 | 8 | 140 |
CA12-25-1400 | 25 | 245 | 1400 | 9.8 | 50 | 245 | 68 |
CA12-25-1064 | 25 | 137 | 1064 | 5.5 | 50 | 137 | 70 |
CA12-25-980 | 25 | 119 | 980 | 4.8 | 50 | 119 | 71 |
CA12-25-950 | 25 | 102 | 950 | 4.1 | 50 | 102 | 72 |
CA12-25-900 | 25 | 96 | 900 | 3.8 | 50 | 96 | 72 |
CA12-25-850 | 25 | 93 | 850 | 3.7 | 50 | 93 | 73 |
CA12-25-808 | 25 | 90 | 808 | 3.6 | 50 | 90 | 73 |
CA12-25-780 | 25 | 87 | 780 | 3.5 | 50 | 87 | 73 |
CA12-25-750 | 25 | 85 | 750 | 3.4 | 50 | 85 | 73 |
CA12-25-700 | 25 | 75 | 700 | 3 | 50 | 75 | 74 |
CA12-25-650 | 25 | 71 | 650 | 2.8 | 50 | 71 | 75 |
CA12-25-600 | 25 | 57 | 600 | 2.3 | 50 | 57 | 77 |
CA12-25-550 | 25 | 34 | 550 | 1.4 | 50 | 34 | 87 |
CA12-40-1064 | 40 | 208 | 850 | 5.2 | 50 | 333 | 44 |
CA12-40-980 | 40 | 180 | 850 | 4.5 | 50 | 288 | 45 |
CA12-40-850 | 40 | 148 | 850 | 3.7 | 50 | 237 | 45 |
CA12-40-808 | 40 | 134 | 808 | 3.4 | 50 | 214 | 46 |
CA12-40-780 | 40 | 124 | 780 | 3.1 | 50 | 198 | 46 |
CA12-40-750 | 40 | 112 | 750 | 2.8 | 50 | 179 | 47 |
CA12-40-700 | 40 | 92 | 700 | 2.3 | 50 | 147 | 48 |
CA12-40-650 | 40 | 80 | 650 | 2 | 50 | 128 | 50 |
CA12-40-600 | 40 | 68 | 600 | 1.7 | 50 | 109 | 51 |
CA12-40-550 | 40 | 60 | 550 | 1.5 | 50 | 96 | 53 |
CA12-50-1064 | 50 | 245 | 1064 | 4.9 | 50 | 490 | 35 |
CA12-50-808 | 50 | 145 | 808 | 2.9 | 50 | 290 | 37 |
CA12-50-700 | 50 | 110 | 700 | 2.2 | 50 | 220 | 39 |
CA12-50-600 | 50 | 100 | 600 | 2 | 50 | 200 | 40 |
CA12-70-750 | 70 | 120 | 750 | 1.7 | 50 | 336 | 29 |
CA12-70-650 | 70 | 105 | 650 | 1.5 | 50 | 294 | 30 |
CA12-70-550 | 70 | 91 | 550 | 1.3 | 50 | 255 | 32 |
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